Definitely doable through wine, although it would be nice to have natie Linux version…
Big tick Rhino synth you mean?
Here’s my result on Renoise native Linux + wine + LinVST bridge, smooth as silk:
That doesn’t look too good 
Howeer, winehq is not set in stone, sometimes it’s database is wonky…so there’s only one way to find out 
Reliability wise - once you find working combination of wine - it’s super reliable with one caveat.
- You should always do portable wineprefix with specific portable wine version
Linux gaming [Guide] will help you to find out pretty much how.
This will not only be reliable, but you can transfer such wineprefix to any other Linux system!
Say you’re insane person with more than 2000 VST plugins like i am…I have it all installed in portable wineprefix…No need to ever re-install it, just backup or transfer whole thing wherever you want.
Basically let’s say you have:
1 wine prefix with perfect configuration and wine version for Ableton Live
1 wine prefix with perfect configuration and wine version for Fusion360 (if you’ll be able to find working conditions)
1 wine prefix for all your vsts