Well, since it works for me it’s certainly not Fedora vs Arch problem at all.
Not sure what exactly is wrong for you, but i think you should try non-system prefix with non-system Wine version, for example POL build
You can use this simple scripts from my gaming guide (read 0. Prepare to 4. Install game) to get how to.
And launch program via exactly same script as install.sh just change the .exe for suitable path (you must launch such .exe through this non-system Wine version of WINELOADER and WINESERVER).
Sorry for inconvenience with this simple scripts, but it’s fastest way to get clean result for now.
Otherwise just try to install clean EnOS in VM and try to figure out what’s going on…
I don’t see anything obvious why it shouldn’t work for you as it works for me 