The PipeWire configuration template file is located in /usr/share/pipewire/pipewire.conf.
You can copy the file to /etc/pipewire/ or ~/.config/pipewire/pipewire.conf and edit it:
Btw, I would not set the default.clock.rate because that would force-resample everything to that specific sampling rate. Using just the allowed-rates would allow the sampling rate to match the current source, so unnecessary resampling would not happen.