As an experiment, I added Fedora to zfs multiboot setup on my primary workstation and tried running it for a month. I had to make some changes to my jobs to accommodate SELinux.
The good news is that the experiment was a success. I had no major problems using Fedora for everything I needed to do. The bad news is I was too lazy busy to modify the jobs on my Arch install and so one month turned into more like 4 months.
On a positive note, I made some scripts to quickly enable and disable all the jobs/services so I can more easily switch back and forth whenever I want to.