I assume that you’ve got an AMD system ?
In terms of gaming in general, there is a meta package arch-gaming-meta within the AUR that should cover almost all bases. I’m not using it on my install as I’m totally fine with proton-ge-custom-bin instead of wine, steam and lutris. Lutris offers their own game-specific database of receipts. And could be also used in combination with steam. For non-gaming purpose, I’m using bottles as well.
Is [multilib] even included in your pacman.conf ?
Other than that, check those :
Within this forum: Linux gaming Guide
Discovery: Gaming-101
Discovery: Steam, Lutris & Wine
Arch Wiki: Gaming
Arch Wiki: Wine